陈维，博士，教授，博士生导师，“新型微纳药物实验室”负责人。2018年入选“江苏特聘教授”， 近年来多次入选美国斯坦福大学发布的全球前2%顶尖科学家。2013年荷兰特文特大学（University of Twente）高分子化学与生物材料专业获博士学位；2013-2017年德国柏林自由大学（Freie Universität Berlin）博士后研究，并荣获德国洪堡学者。目前已在化学、药学、生物材料学等领域国际知名学术期刊如：Angew. Chem. Int. Ed.、Adv. Funct. Mater.、APSB、J. Control. Release、Biomaterials、Nano Today等发表论文70余篇，论文引用3500余次。目前已申请或授权的欧洲、美国专利和中国专利30余项，主持多项省部级、校级和企业转化科研项目。

   智能型可降解微纳药物、功能性生物材料合成加工、药效分子高效分离提取

面上项目，国家自然科学基金委，促进血脑屏障跨越及药物深层渗透的两性离子型NO供体纳米药物用于脑肿瘤的靶向联合治疗，2025.01-2028.12。

面上项目，国家自然科学基金委，生物响应性小尺寸两性离子纳米药物促进肿瘤高效富集与渗透及对干细胞的治疗，2022.01-2025.12。

面上项目，国家自然科学基金委，含一氧化氮供体的生物可降解可逆交联胶束介导前列腺癌靶向协同治疗，2020.01-2023.12。

青年项目，国家自然科学基金委，肿瘤高靶向的不对称膜结构的两性离子聚合物囊泡用于蛋白质药物的高效包裹和控制释放，2018.01-2021.01。

青年项目，江苏省自然科学基金委，低免疫原性的不对称膜结构的聚合物囊泡用于蛋白质药物的高效包封与肿瘤靶向治疗，2017.07-2020.07。

1. J.M. Zhang, G.Z. Miao, M.H. Ta, B.B. Zhao, W. Wang, Y.R. Xing, H.L. Qian, D.C. Huang*, W. Chen*, Y.N. Zhong*, Photothermal-controlled NO-releasing Nanogels Reverse Epithelial-mesenchymal Transition and Restore Immune Surveillance against Cancer Metastasis, J. Control. Release 2024, 371, 16-28.

2. L.L. Gao, Z.Y. Yuan, N.Y. Ma, X. Zhou, X. Huang, W. Chen*, H.S. Qiao*, Nitric Oxide Polymersome-Immobilized Hydrogels for Prevention of Post-surgical Tumor Recurrence and Metastasis, Chem. Eng. J. 2024, 485, 149688.

3. Y.H. Ma, C.H. Li, F.W. Han, Y.Z. Liu, U.E. Hani, Y.N. Zhong, D.C. Huang*, W. Chen*, H.L. Qian*, Oral Delivery Of Berberine by Liver-Targeted Zwitterionic Nanoparticles to Overcome Multi-Intestinal Barriers and Extend Insulin Treatment Duration, Chem. Eng. J. 2024, 485, 150129.

4. K. Wang#, B.B. Zhao#, Y.L. Ao, J.Y. Zhu, C.S. Zhao, W. Wang, Y. Zou, D.C. Huang*, Y.N. Zhong, W. Chen*, H.L. Qian*, Super-small Zwitterionic Micelles Enable the Improvement of Blood-brain Barrier Crossing for Efficient Orthotopic Glioblastoma Combinational Therapy, J. Control. Release 2023, 364, 261-271.

5. Y.F. Li#, H.L. Qian#, X. Huang#, X. Zhou, B.B. Zhao, L.F. Yang, J.X. Chen, H.S. Qiao, D.C. Huang*, Y.N. Zhong*, W. Chen*, Up-Converted Nano-Gasholder with Precise Nitric Oxide Release Remodels Immunosuppressive Microenvironment and Potentiates Tumor Immunotherapy, Nano Today 2022, 42, 101381.

6. H.L. Qian#, K. Wang#, M.T. Lv, C.S. Zhao, H. Wang, S.C. Wen, D.C. Huang*, W. Chen*, Y.N. Zhong*, Recent Advances on Next Generation of Polyzwitterion-based Nano-Vectors for Targeted Drug Delivery, J. Control. Release 2022, 343, 492-505.

7. Z.H. Liu#, Y.N. Zhong#, X. Zhou, X. Huang, J.J. Zhou, D.C. Huang*, Y.F. Li, Z.X. Wang, B. Dong, H.S. Qiao*, W. Chen*, Inherently Nitric Oxide Containing Polymersomes Remotely Regulated by NIR for Improving Multi-Modal Therapy on Drug Resistant Cancer, Biomaterials 2021, 277, 121118.

8. Y.N. Zhong*, J.G. Zhang, J.M. Zhang, Y. Hou, E.P. Chen, D.C. Huang, W. Chen*, R. Haag*, Tumor Microenvironment-Activatable Nanoenzymes for Mechanical Remodeling of Extracellular Matrix and Enhanced Tumor Chemotherapy, Adv. Funct. Mater. 2021, 31, 2007544.

9. Q. Zhao#, S.Y. Zhang#, F.C. Wu, D.Y. Li, X.J. Zhang*, W. Chen*, B.S. Xing*, Rational Design of Nanogels for Overcoming the Biological Barriers in Various Administration Routes, Angew. Chem. Int. Ed. 2021, 60, 2-20.

10. Z.X. Tu, I.S. Donskyi, H.S. Qiao, Z.L. Zhu, W.E.S. Unger, C.P.R. Hackenberger, W. Chen*, M. Adeli*, and R. Haag*, Graphene Oxide-Cyclic R10 Peptide Nuclear Translocation Nanoplatforms for the Surmounting of Multiple-Drug Resistance, Adv. Funct. Mater. 2020, 2000933.