钟伊南,女,博士,2018年以特聘副研究员引进,现为博士研究生导师,就职于工学院制药工程教研室。以第一作者或通讯作者在药剂学、化学、生物材料相关领域的国际著名学术期刊如:Adv. Func. Mater.、J. Control. Release、Biomaterials、ACS Appl. Mater. Interfaces等发表论文15篇(包括3篇ESI高被引论文),文章引用1400余次。获得国家发明专利1项并已成功转让。主持国家自然科学基金青年项目以及企业合作横向项目(200万)等。
研究方向
智能纳米药物的制备及体内外应用
多功能生物材料用于多种疾病微环境调控及治疗
代表性科研成果
1. Y.N. Zhong,* J.G. Zhang, J.M. Zhang, Y. Hou, E.P. Chen, D.C. Huang, W. Chen,* and R. Haag*, Tumor Microenvironment-Activatable Nanoenzymes for Mechanical Remodeling of Extracellular Matrix and Enhanced Tumor Chemotherapy, Advanced Functional Materials, 2021, 31, 2007544.
2. Y.N. Zhong, F.H. Meng*, W. Zhang, B. Li, J. C. M. van Hest, Z.Y. Zhong*, CD44-Targeted Vesicles Encapsulating Granzyme B as Artificial Killer Cells for Potent Inhibition of Human Multiple Myeloma in Mice, Journal of Controlled Release, 2020, 320, 421–430.
3. Y.N. Zhong, K. Goltsche, L. Cheng, F. Xie, F.H. Meng**, C. Deng, Z.Y. Zhong*, R. Haag, Hyaluronic Acid-Shelled Acid-Activatable Paclitaxel Prodrug Micelles Effectively Target and Treat CD44-Overexpressing Human Breast Tumor Xenografts In Vivo, Biomaterials, 2016, 84, 250-261. (SCI他引149次, ESI高被引论文)
4. Y.N. Zhong, M. Dimde, D. Stöbener, F.H. Meng*, C. Deng, Z.Y. Zhong*, R. Haag, Micelles with Sheddable Dendritic Polyglycerol Sulfate Shells Show Extraordinary Tumor Targetability and Chemotherapy In Vivo, ACS Applied Materials & Interfaces, 2016, 8 (41), 27530–27538.
5. Y.N. Zhong, J. Zhang, R. Cheng*, C. Deng, F.H. Meng, F. Xie*, Z.Y. Zhong*, Reversibly Crosslinked Hyaluronic Acid Nanoparticles for Active Targeting and Intelligent Delivery of Doxorubicin to Drug Resistant CD44+ Human Breast Tumor Xenografts, Journal of Controlled Release, 2015, 205, 144–154. (SCI他引164次, ESI高被引论文, 2016和2017年度ESI热点论文)
6. Y.N. Zhong, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Ligand-Directed Active Tumor-Targeting Polymeric Nanoparticles for Cancer Chemotherapy, Biomacromolecules, 2014, 15, 1955−1969. (SCI他引269次, ESI高被引论文)
7. 专利:钟志远,钟伊南,孟凤华,基于透明质酸的两亲聚合物、其制备方法与应用,201510006737.9(已转让)
联系方式
诚邀具有有机化学、高分子化学、药学、生物医学等研究背景的学生加入课题研究(邮箱:zhongyinan@126.com;手机:18862196332)。
招生代码
博士:1007Z1制药工程学;学硕:1007Z1制药工程学00不区分研究方向;专硕:086000生物与医药 02制药工程与工艺