刘熠，男，博士，教授，博士生导师，现工作于工学院生物医学工程与诊断药学系。博士毕业于复旦大学化学系黄春辉院士和李富友教授课题组。随后在美国国立卫生研究院（NIH）陈小元课题组从事博士后工作。主持国家自然科学基金3项和江苏省自然科学基金，入选江苏省“六大人才高峰”和“333高层次”人才项目。以第一作者或通讯作者身份在JACS，Adv. Mater.和Adv. Sci.等国际权威期刊发表高水平SCI论文60余篇，获得授权专利5项。应邀成为ACS Nano，Chem. Sci.和Adv. Sci.等专业杂志的审稿人；撰写《诊断试剂原理与制备》的教材；被聘为中国生物医学工程生物光子分会青年委员和中国医药生物技术协会纳米生物技术分会委员。

招生方向：

学硕：生物医学工程

专硕：生物与医药（生物材料与诊断试剂）

学博：生物医学工程

1.小分子探针用于病理靶标分子的体外诊断和活体监测。

2.响应型有机功能材料用于疾病的早期诊断和精准治疗。

1. 国家科学基金面上项目（81771900, 82272148 ）；

2. 国家科学基金青年项目（81601531）；

3. 江苏省青年科学基金项目（BK20160755）；

4. 江苏省“六大人才高峰”项目（SWYY-063）；

5. 中国药科大学人才引进启动经费

1. Chai, Y.; Xu, M.; Sun, Y.; Zhu, Y.; Du, T.; Zhu, B.; Yu, H.; Sun, X.; Pan, Y.; Liu, Y.* Hydrogen sulfide-responsive and depleting NIR-II nanoplatform synergistic photodynamic therapy for colorectal cancer. Chem. Eng. J., 2025, 510, 161711.

2. Liu, J.; Lu, Y.; Tian, Y.; Liu, Q.; Sun, X.; Liu, Y. *; Lei, Y. A Light-Activatable Nitric Oxide Donor for Targeted Glaucoma Therapy with Real-Time Monitoring Capabilities. Adv. Healthcare Mater., 2025, 14 (11), 2404221.

3. Sun, Y.; Wang, J.; Zhu, Y.; Han, T.; Liu, Y.*; Wang, H.-Y. Nanoprobes based on optical imaging techniques for detecting biomarkers in liver injury diseases. Coord. Chem. Rev., 2025, 524, 216303.

4. Chai, Y.; Shangguan, L.; Yu, H.; Sun, Y.; Huang, X.; Zhu, Y.; Wang, H.-Y.; Liu, Y.* Near Infrared Light-Activatable Platelet-Mimicking NIR-II NO Nano-Prodrug for Precise Atherosclerosis Theranostics. Adv. Sci., 2024, 11 (3), 2304994.

5. Han, T.; Sun, Y.; Zhao, C.; Wang, H.-Y.; Yu, H.; Liu, Y.* Mitochondrial-Targeted Ratiometric Near-Infrared Fluorescence Probe for Monitoring Nitric Oxide in Rheumatoid Arthritis. J. Med. Chem., 2024, 67 (5), 4026-4035.

6. Zhao, C.; Sun, W.; Zhu, Y.; Huang, X.; Sun, Y.; Wang, H.-Y.; Pan, Y.; Liu, Y.* An Activatable Heavy-Atom-Free Upconversion Photosensitizer for Targeted Imaging and Treatment of Tumors. J. Med. Chem., 2024, 67 (24), 22322-22331.

7. Yu, H.; Tiemuer, A.; Yao, X.; Zuo, M.; Wang, H.-Y.; Liu, Y.*; Chen, X. Mitochondria-specific near-infrared photoactivation of peroxynitrite upconversion luminescent nanogenerator for precision cancer gas therapy. Acta Pharm. Sin. B, 2024, 14 (1), 378-391.

8. Chai, Y.; Sun, Y.; Sheng, Z.; Zhu, Y.; Du, T.; Zhu, B.; Yu, H.; Dong, B.; Liu, Y.*; Wang, H.-Y. Reversible pH-switchable NIR-II nano-photosensitizer for precise imaging and photodynamic therapy of tumors. Acta Biomater, 2024, 188, 315-328.

9. Zhao, C.; Sun, W.; Huang, X.; Liu, Y.*; Wang, H.-Y. Alkaline Phosphatase Activated Near-Infrared Frequency Upconversion Photosensitizers for Tumor Photodynamic Therapy. J. Med. Chem., 2024, 67 (15), 13383-13391.

10. Chen, S.; Wang, J.; Guan, D.; Tan, B.; Zhai, T.; Yang, L.; Han, Y.; Liu, Y. *; Liu, Q.; Zhang, Y. Near-Infrared Spontaneously Blinking Fluorophores for Live Cell Super-Resolution Imaging with Minimized Phototoxicity. Anal. Chem., 2024, 96 (26), 10860-10869.

11. Tan, B.; Zhao, C.; Wang, J.; Tiemuer, A.; Zhang, Y.; Yu, H.; Liu, Y.* Rational design of pH-activated upconversion luminescent nanoprobes for bioimaging of tumor acidic microenvironment and the enhancement of photothermal therapy. Acta Biomater., 2023, 155, 554-563.

12. Yu, H.; Chai, Y.; Tiemuer, A.; Han, Y.; Wang, H.-Y.; Liu, Y.* Frequency upconversion luminescence: New frontiers in bioapplications. Coord. Chem. Rev., 2023, 496, 215379.

13. Wang, J.; Sheng, Z.; Guo, J.; Wang, H.-Y.; Sun, X.; Liu, Y.* Near-Infrared Fluorescence Probes for Monitoring and Diagnosing Nephron-Urological Diseases. Coord. Chem. Rev., 2023, 486, 215137.

14. Wang, K.; Zhang, X.; Cheng, Y.; Qi, Z.; Ye, K.; Zhang, K.; Jiang, S.; Liu, Y. *; Xiao, Y.; Wang, T. Discovery of Novel PD-L1 Inhibitors That Induce the Dimerization, Internalization, and Degradation of PD-L1 Based on the Fragment Coupling Strategy. J. Med. Chem., 2023, 66 (24), 16807-16827.

15. Tiemuer A.; Yu, H.; Zhao, C.; Sun, W. L.; Zhang, Y. Y.; Jiang, Y. M.; Gu, Y. Q.; Liu, Y. *Nitroso-Caged Upconversion Luminescent Prodrug: Near Infrared Light-Activatable NO Nano-Donor for Gas Therapy. Chem. Eng. J., 2022, 132858.

16. Zhou, F. Y.; Yang, S. K.; Zhao, C.; Liu, W. W.; Yao, X. F.; Yu, H.; Sun, X. L.; Liu, Y. * γ-Glutamyl transpeptidase-activatable near-infrared nanoassembly for tumor fluorescence imaging-guided photothermal therapy. Theranostics, 2021, 11(14): 7045-7056.

17. Ma, Yi; Ma, Y. Y.; Gao, M. Q.; Han, Z. H.; Jiang, W; Gu, Y. Q.*; Liu, Y.* Platelet‐Mimicking Therapeutic System for Noninvasive Mitigation of the Progression of Atherosclerotic Plaques. Adv. Sci., 2021, DOI: 10.1002/advs.202004128.

18. Liu, Y.; Chen, M.; Cao, T. Y.; Sun. Y.; Li, C. Y.; Liu, Q.; Yang, T. S.; Yao, L. M.; Feng, W.; Li, F. Y.* A Cyanine-Modified Nanosystem for in Vivo Upconversion Luminescence Bioimaging of Methylmercury, J. Am. Chem. Soc., 2013, 135, 9869. 

19. Liu,Y.; Su, Q. Q.; Chen, M.; Dong, Y.; Shi, Y. B.; Feng, W.; Wu, Z-Y.; Li, F. Y.* Near-Infrared Upconversion Chemodosimeter for in Vivo Detection of Cu²⁺ in Wilson Disease. Adv. Mater., 2016, 28, 6625.

20. Liu, Y.; Wang, S.; Ma, Y.; Lin, J.; Wang, H.; Gu, Y. Q.*; Chen, X. Y.*; Huang, P.* Ratiometric Photoacoustic Molecular Imaging for Methylmercury Detection in Living Subjects, Adv. Mater., 2017, DOI: 10.1002/adma.201606129